Chloroprocaine Hydrochloride has 5 known drug interactions based on U.S. FDA drug labeling data. Of these, 1 are contraindicated combinations that should be avoided entirely. 4 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Acetazolamide, Ergot-Type Oxytocic Drugs, Monoamine Oxidase Inhibitors (Maois). Patients taking Chloroprocaine Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 5
- Contraindicated
- 1
- Major
- 4
Contraindicated (1)
- Chloroprocaine Hydrochloride + Acetazolamide— Chloroprocaine should not be used when sulfonamide drugs are being employed. The para-aminobenzoic acid metabolite of ch…
Major (4)
- Chloroprocaine Hydrochloride + Ergot-Type Oxytocic Drugs— Concurrent administration with vasopressor drugs may cause severe, persistent hypertension or cerebrovascular accidents.
- Chloroprocaine Hydrochloride + Monoamine Oxidase Inhibitors (Maois)— Concurrent use with local anesthetic solutions containing epinephrine or norepinephrine may produce severe, prolonged hy…
- Chloroprocaine Hydrochloride + Phenothiazines— Concurrent use with local anesthetic solutions containing epinephrine or norepinephrine may produce severe, prolonged hy…
- Chloroprocaine Hydrochloride + Vasopressin— Concurrent administration with ergot-type oxytocic drugs may cause severe, persistent hypertension or cerebrovascular ac…