Oxybutynin Chloride has 6 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Ketoconazole, Clarithromycin, Erythromycin. Patients taking Oxybutynin Chloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 6
- Major
- 1
- Moderate
- 5
Major (1)
- Oxybutynin Chloride + Ketoconazole— Mean oxybutynin chloride plasma concentrations were approximately 3 to 4 fold higher when co-administered with ketoconaz…
Moderate (5)
- Oxybutynin Chloride + Clarithromycin— Macrolide antibiotic and CYP3A4 inhibitor that may alter oxybutynin mean pharmacokinetic parameters (Cmax and AUC). Caut…
- Oxybutynin Chloride + Erythromycin— Macrolide antibiotic and CYP3A4 inhibitor that may alter oxybutynin mean pharmacokinetic parameters (Cmax and AUC). Caut…
- Oxybutynin Chloride + Itraconazole— Antimycotic agent and CYP3A4 inhibitor that may alter oxybutynin mean pharmacokinetic parameters (Cmax and AUC). Caution…
- Oxybutynin Chloride + Metoclopramide— Anticholinergic agents may antagonize the effects of prokinetic agents such as metoclopramide.
- Oxybutynin Chloride + Miconazole— Antimycotic agent and CYP3A4 inhibitor that may alter oxybutynin mean pharmacokinetic parameters (Cmax and AUC). Caution…