Ketoconazole has been reported to decrease the metabolism of certain corticosteroids by up to 60% leading to an increased risk of corticosteroid side effects.
Source: FDA drug label - prednisolone sodium phosphate
Prednisolone Sodium Phosphate Interactions
Brand names: Prednisolone Sodium Phosphate
2 interactions on record
Drug Interactions Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Prednisolone Sodium Phosphate Oral Solution (15 mg Prednisolone per 5 mL) be increased.
Source: FDA drug label - prednisolone sodium phosphate