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Imipenem

Also known as: Recarbrio, Primaxin

4 interactions on record

Imipenem has 4 known drug interactions based on U.S. FDA drug labeling data. 4 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Divalproex Sodium, Divalproex Sodium Er, Duloxetine D/R. Patients taking Imipenem should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 4
Major: 4

Major (4)

Imipenem + Divalproex Sodium— Carbapenem antibiotic that causes clinically significant reduction in serum valproic acid concentration and may result i…
Imipenem + Divalproex Sodium Er— Clinically significant reduction in serum valproic acid concentration reported, potentially resulting in loss of seizure…
Imipenem + Duloxetine D/R— Carbapenem antibiotic causing clinically significant reduction in serum valproic acid concentration, potentially resulti…
Imipenem + Valproic Acid— Carbapenem antibiotic causing clinically significant reduction in serum valproic acid concentration, potentially resulti…

Imipenem + Divalproex Sodium⚠️Major

Carbapenem antibiotic that causes clinically significant reduction in serum valproic acid concentration and may result in loss of seizure control.

Imipenem + Divalproex Sodium Er⚠️Major

Clinically significant reduction in serum valproic acid concentration reported, potentially resulting in loss of seizure control.

Imipenem + Duloxetine D/R⚠️Major

Carbapenem antibiotic causing clinically significant reduction in serum valproic acid concentration, potentially resulting in loss of seizure control.

Imipenem + Valproic Acid⚠️Major

Carbapenem antibiotic causing clinically significant reduction in serum valproic acid concentration, potentially resulting in loss of seizure control.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.