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Penciclovir

Also known as: Denavir

Herpesvirus Nucleoside Analog DNA Polymerase InhibitorDNA Polymerase Inhibitors

Route: Topical

2 interactions on record

Penciclovir has 2 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Famciclovir. Patients taking Penciclovir should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 2
Moderate: 1
Minor: 1

Moderate (1)

Penciclovir + Famciclovir— 7 DRUG INTERACTIONS Probenecid: May increase penciclovir levels. Monitor for evidence of penciclovir toxicity. 7.2 Poten…

Minor (1)

Penciclovir + Denavir— 7 DRUG INTERACTIONS No drug interaction studies have been performed with DENAVIR. Due to minimal systemic absorption of …

Penciclovir + Famciclovir🟡Moderate

7 DRUG INTERACTIONS Probenecid: May increase penciclovir levels. Monitor for evidence of penciclovir toxicity. 7.2 Potential for Other Drugs to Affect Penciclovir No clinically significant alterations in penciclovir pharmacokinetics were observed following single-dose administration of 500 mg famciclovir after pretreatment with multiple doses of allopurinol, cimetidine, theophylline, zidovudine, promethazine, when given shortly after an antacid (magnesium and aluminum hydroxide), or concomitantly with emtricitabine.

Penciclovir + Denavir🟢Minor

7 DRUG INTERACTIONS No drug interaction studies have been performed with DENAVIR. Due to minimal systemic absorption of DENAVIR, systemic drug interactions are unlikely.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.