Adapalene + ResorcinolModerate
Particular caution advised when using resorcinol preparations with adapalene cream due to potential for increased local irritation.
Source: NLP:adapalene
Adapalene Interactions
Brand names: Adapalene
Retinoid
Route: Topical
Contraindications
CONTRAINDICATIONS Adapalene Topical Solution, 0.1% should not be administered to individuals who are hypersensitive to adapalene or any of the components in the vehicle solution.
Pregnancy & Breastfeeding
Pregnancy Teratogenic effects Pregnancy Category C No teratogenic effects were seen in rats at oral doses of adapalene 0.15 to 5.0 mg/kg/day, up to 120 times the maximal daily human topical dose. Cutaneous route teratology studies conducted in rats and rabbits at doses of 0.6, 2.0, and 6.0 mg/kg/day, up to 150 times the maximal daily human topical dose exhibited no fetotoxicity and only minimal increases in supernumerary ribs in rats. There are no adequate well-controlled studies in pregnant women. Adapalene should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
3 interactions on record
Adapalene + Salicylic AcidModerate
Particular caution advised when using salicylic acid preparations with adapalene cream due to potential for increased local irritation.
Source: NLP:adapalene
Adapalene + SulfurModerate
Particular caution advised when using sulfur preparations with adapalene cream due to potential for increased local irritation.
Source: NLP:adapalene