Isoproterenol has 5 known drug interactions based on U.S. FDA drug labeling data. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Carbidopa, Levodopa And Entacapone, Cromolyn Sodium, Nicotine. Patients taking Isoproterenol should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 5
- Major
- 2
- Moderate
- 3
Major (2)
- Isoproterenol + Carbidopa, Levodopa And Entacapone— May result in increased heart rates, possibly arrhythmias, and excessive changes in blood pressure. Metabolized by COMT.
- Isoproterenol + Cromolyn Sodium— In pregnant mice, combined use increased incidence of major malformations (primarily cleft palate) beyond effects of iso…
Moderate (3)
- Isoproterenol + Nicotine— Smoking cessation with nicotine replacement may require dose increase due to decreased circulating catecholamines.
- Isoproterenol + Sotalol Hydrochloride— Beta-agonist; may require increased dosages when used concomitantly with sotalol.
- Isoproterenol + Tolcapone— Tolcapone may influence pharmacokinetics of COMT substrates like isoproterenol. Dose reduction should be considered when…