Isosorbide Dinitrate has 3 known drug interactions based on U.S. FDA drug labeling data. Of these, 2 are contraindicated combinations that should be avoided entirely. Notable interactions include combinations with Mao Inhibitors, Riociguat, Alcohol. Patients taking Isosorbide Dinitrate should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 3
- Contraindicated
- 2
- Moderate
- 1
Contraindicated (2)
- Isosorbide Dinitrate + Mao Inhibitors— Concomitant use of isosorbide dinitrate with phosphodiesterase inhibitors in any form is contraindicated.
- Isosorbide Dinitrate + Riociguat— Concomitant use of isosorbide dinitrate with riociguat, a soluble guanylate cyclase stimulator, is contraindicated.
Moderate (1)
- Isosorbide Dinitrate + Alcohol— Alcohol exhibits additive vasodilating effects with isosorbide dinitrate.