Furosemide, Benzalkonium Chloride has 16 known drug interactions based on U.S. FDA drug labeling data. Of these, 1 are contraindicated combinations that should be avoided entirely. 6 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Ethacrynic Acid, Angiotensin Ii, Chloral Hydrate. Patients taking Furosemide, Benzalkonium Chloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 16
- Contraindicated
- 1
- Major
- 6
- Moderate
- 7
Contraindicated (1)
- Furosemide, Benzalkonium Chloride + Ethacrynic Acid— Furosemide should not be used concomitantly with ethacrynic acid because of the possibility of ototoxicity.
Major (6)
- Furosemide, Benzalkonium Chloride + Angiotensin Ii— Furosemide combined with ACE inhibitors may lead to severe hypotension and deterioration in renal function, including re…
- Furosemide, Benzalkonium Chloride + Chloral Hydrate— Intravenous furosemide within 24 hours of chloral hydrate may cause flushing, sweating, restlessness, nausea, hypertensi…
- Furosemide, Benzalkonium Chloride + Cisplatin— Risk of ototoxic effects if cisplatin and furosemide are given concomitantly. Nephrotoxicity may be enhanced if furosemi…
- Furosemide, Benzalkonium Chloride + Lithium— Lithium should not be given with furosemide because diuretics reduce lithium's renal clearance and add a high risk of li…
- Furosemide, Benzalkonium Chloride + Macrolide Antibiotics— Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired ren…
- Furosemide, Benzalkonium Chloride + Salicylates— Patients receiving high doses of salicylates concomitantly with furosemide may experience salicylate toxicity at lower d…
Moderate (7)
- Furosemide, Benzalkonium Chloride + Adrenergic Blockers— Potentiation occurs with ganglionic or peripheral adrenergic blocking drugs.
- Furosemide, Benzalkonium Chloride + Methotrexate— Methotrexate and other drugs undergoing significant renal tubular secretion may reduce the effect of furosemide and furo…
- Furosemide, Benzalkonium Chloride + Norepinephrine— Furosemide may decrease arterial responsiveness to norepinephrine, though norepinephrine may still be used effectively.
- Furosemide, Benzalkonium Chloride + Phenytoin— Phenytoin interferes directly with renal action of furosemide and decreases intestinal absorption, leading to lower peak…
- Furosemide, Benzalkonium Chloride + Succinylcholine— Furosemide may potentiate the action of succinylcholine.
- Furosemide, Benzalkonium Chloride + Sucralfate— Simultaneous administration of sucralfate and furosemide tablets may reduce the natriuretic and antihypertensive effects…
- Furosemide, Benzalkonium Chloride + Tubocurarine— Furosemide has a tendency to antagonize the skeletal muscle-relaxing effect of tubocurarine.