Methazolamide has 5 known drug interactions based on U.S. FDA drug labeling data. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Acetylsalicylic Acid, Aspirin (High-Dose), Steroid Therapy. Patients taking Methazolamide should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 5
- Major
- 2
- Moderate
- 2
Major (2)
- Methazolamide + Acetylsalicylic Acid— High-dose aspirin with methazolamide may cause anorexia, tachypnea, lethargy, coma, and death. Caution advised with conc…
- Methazolamide + Aspirin (High-Dose)— Concomitant use may cause anorexia, tachypnea, lethargy, coma, and death; caution advised with high-dose aspirin.
Moderate (2)
- Methazolamide + Steroid Therapy— Potential for developing hypokalemia when used concomitantly with methazolamide; caution advised.
- Methazolamide + Topical Steroids— Concomitant use may lead to hypokalemia development. Use with caution and monitor potassium levels.