Epinephrine In Sodium Chloride has 21 known drug interactions based on U.S. FDA drug labeling data. 8 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Cardiac Glycosides, Cyclopropane, Digitalis Glycosides. Patients taking Epinephrine In Sodium Chloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 21
- Major
- 8
- Moderate
- 13
Major (8)
- Epinephrine In Sodium Chloride + Cardiac Glycosides— Increase the arrhythmogenic potential of epinephrine; patients should be observed carefully for cardiac arrhythmias.
- Epinephrine In Sodium Chloride + Cyclopropane— Anesthetic that increases the arrhythmogenic potential of epinephrine.
- Epinephrine In Sodium Chloride + Digitalis Glycosides— Cardiac glycosides that increase arrhythmogenic potential of epinephrine. Monitor for cardiac arrhythmias.
- Epinephrine In Sodium Chloride + Halothane— Halogenated hydrocarbon anesthetic that increases arrhythmogenic potential of epinephrine.
- Epinephrine In Sodium Chloride + Mao Inhibitors— Potentiate the pressor effects of epinephrine.
- Epinephrine In Sodium Chloride + Propranolol— Beta blocker that potentiates pressor effects and increases arrhythmogenic potential of epinephrine.
- Epinephrine In Sodium Chloride + Quinidine— Increases the arrhythmogenic potential of epinephrine; patients should be observed carefully for cardiac arrhythmias.
- Epinephrine In Sodium Chloride + Thyroid Hormones— Increase arrhythmogenic potential of epinephrine. Monitor for cardiac arrhythmias.
Moderate (13)
- Epinephrine In Sodium Chloride + Antihistamines— Potentiate epinephrine effects and increase arrhythmogenic potential.
- Epinephrine In Sodium Chloride + Clonidine— Potentiates the effects of epinephrine.
- Epinephrine In Sodium Chloride + Corticosteroids— Potentiate the hypokalemic effects of epinephrine.
- Epinephrine In Sodium Chloride + Diuretics— Counter pressor effects, increase arrhythmogenic potential, and potentiate hypokalemic effects of epinephrine.
- Epinephrine In Sodium Chloride + Doxapram— Potentiates the effects of epinephrine.
- Epinephrine In Sodium Chloride + Entacapone— COMT inhibitor that potentiates the effects of epinephrine.
- Epinephrine In Sodium Chloride + Ergot Alkaloids— Counter the pressor effects of epinephrine.
- Epinephrine In Sodium Chloride + Levothyroxine Sodium— Potentiates the pressor effects of epinephrine.
- Epinephrine In Sodium Chloride + Nitrates— Vasodilator that counters the pressor effects of epinephrine.
- Epinephrine In Sodium Chloride + Oxytocin— Potentiates the effects of epinephrine.
- Epinephrine In Sodium Chloride + Phenothiazine Antipsychotics— Antipsychotics that antagonize the pressor effects of epinephrine.
- Epinephrine In Sodium Chloride + Phentolamine— Alpha blocker that counters the pressor effects of epinephrine.
- Epinephrine In Sodium Chloride + Theophylline— Potassium-depleting drug that potentiates the hypokalemic effects of epinephrine.