Metyrapone has 6 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Acetaminophen, Acidifying Agents, Corticosteroids. Patients taking Metyrapone should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 6
- Major
- 1
- Moderate
- 5
Major (1)
- Metyrapone + Acetaminophen— Metyrapone inhibits glucuronidation of acetaminophen, decreasing elimination and increasing risk of adverse reactions. A…
Moderate (5)
- Metyrapone + Acidifying Agents— May affect the results of the metyrapone test. Consider withdrawing if possible before testing.
- Metyrapone + Corticosteroids— May affect the results of the metyrapone test. Consider withdrawing if possible before testing.
- Metyrapone + Cyproheptadine— May affect the results of the metyrapone test. Consider withdrawing if possible before testing.
- Metyrapone + Oral Anticoagulants— May affect the results of the metyrapone test. Consider withdrawing if possible before testing.
- Metyrapone + Parathyroid Hormone— May affect the results of the metyrapone test. Consider withdrawing if possible before testing.