Phenoxybenzamine Hydrochloride has 3 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Epinephrine, Norepinephrine Bitartrate, Reserpine. Patients taking Phenoxybenzamine Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 3
- Major
- 1
- Moderate
- 2
Major (1)
- Phenoxybenzamine Hydrochloride + Epinephrine— May produce exaggerated hypotensive response and tachycardia due to alpha- and beta-adrenergic receptor stimulation.
Moderate (2)
- Phenoxybenzamine Hydrochloride + Norepinephrine Bitartrate— Phenoxybenzamine blocks hyperthermia production by levarterenol.
- Phenoxybenzamine Hydrochloride + Reserpine— Phenoxybenzamine blocks hypothermia production by reserpine.