Eltrombopag Olamine has 27 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Atorvastatin, Bosentan, Ezetimibe. Patients taking Eltrombopag Olamine should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 27
- Moderate
- 20
- Minor
- 5
Moderate (20)
- Eltrombopag Olamine + Atorvastatin— 7.2 Transporters Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., a…
- Eltrombopag Olamine + Bosentan— OATP1B1 substrate; monitor for excessive exposure and consider dose reduction if appropriate.
- Eltrombopag Olamine + Ezetimibe— OATP1B1 substrate; monitor for excessive exposure and consider dose reduction if appropriate.
- Eltrombopag Olamine + Fluvastatin— 7.2 Transporters Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., a…
- Eltrombopag Olamine + Glibenclamide— OATP1B1 substrate; monitor for excessive exposure and consider dose reduction if appropriate.
- Eltrombopag Olamine + Imatinib— 7.2 Transporters Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., a…
- Eltrombopag Olamine + Irinotecan— BCRP substrate (active metabolite SN-38); monitor for excessive exposure and consider dose reduction if appropriate.
- Eltrombopag Olamine + Lapatinib— 7.2 Transporters Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., a…
- Eltrombopag Olamine + Methotrexate— BCRP substrate; monitor for excessive exposure and consider dose reduction if appropriate.
- Eltrombopag Olamine + Mitoxantrone— BCRP substrate; monitor for excessive exposure and consider dose reduction if appropriate.
- Eltrombopag Olamine + Olmesartan— 7.2 Transporters Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., a…
- Eltrombopag Olamine + Pitavastatin— 7.2 Transporters Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., a…
- Eltrombopag Olamine + Pravastatin— 7.2 Transporters Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., a…
- Eltrombopag Olamine + Repaglinide— OATP1B1 substrate; monitor for excessive exposure and consider dose reduction if appropriate.
- Eltrombopag Olamine + Rifampin— OATP1B1 substrate; monitor for excessive exposure and consider dose reduction if appropriate.
- Eltrombopag Olamine + Rosuvastatin— 7.2 Transporters Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., a…
- Eltrombopag Olamine + Simvastatin— 7.2 Transporters Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., a…
- Eltrombopag Olamine + Sulfasalazine— BCRP substrate; monitor for excessive exposure and consider dose reduction if appropriate.
- Eltrombopag Olamine + Topotecan— BCRP substrate; monitor for excessive exposure and consider dose reduction if appropriate.
- Eltrombopag Olamine + Valsartan— 7.2 Transporters Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., a…
Minor (5)
- Eltrombopag Olamine + Boceprevir— No dose adjustment recommended when coadministered with eltrombopag.
- Eltrombopag Olamine + Lopinavir And Ritonavir— No dose adjustment recommended when coadministered with eltrombopag.
- Eltrombopag Olamine + Peginterferon Alfa-2a— No dose adjustment recommended when coadministered with eltrombopag.
- Eltrombopag Olamine + Peginterferon Alfa-2b— No dose adjustment recommended when coadministered with eltrombopag.
- Eltrombopag Olamine + Telaprevir— No dose adjustment recommended when coadministered with eltrombopag.