Pancuronium Interactions

Neuromuscular blocking agent. Concomitant use with deflazacort may increase risk of developing acute myopathy.

Source: NLP:deflazacort

Pancuronium and vecuronium may manifest additive neuromuscular blocking effects when used together due to similar mechanism of action.

Source: NLP:vecuronium bromide

Desflurane reduces ED95 of pancuronium by approximately 50%. Dose adjustment may be needed during maintenance anesthesia.

Source: NLP:desflurane

Isoflurane potentiates the muscle relaxant effect of pancuronium, reducing required ED95 by approximately 25-40%. Dose adjustment required.

Source: NLP:isoflurane

Sevoflurane increases both the intensity and duration of neuromuscular blockade induced by pancuronium. Dosage adjustments required.

Source: NLP:sevoflurane

May increase serum concentration of trospium and/or pancuronium due to competition for renal tubular secretion. Careful patient monitoring is recommended.

Source: NLP:trospium chloride