Papaverine has 5 known drug interactions based on U.S. FDA drug labeling data. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Carbidopa And Levodopa, Carbidopa, Levodopa And Entacapone, Carbidopa. Patients taking Papaverine should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 5
- Major
- 2
- Moderate
- 3
Major (2)
- Papaverine + Carbidopa And Levodopa— The beneficial effects of levodopa in Parkinson's disease have been reported to be reversed by papaverine.
- Papaverine + Carbidopa, Levodopa And Entacapone— Beneficial effects of levodopa in Parkinson's disease have been reported to be reversed by papaverine.
Moderate (3)
- Papaverine + Carbidopa— Beneficial effects of levodopa in Parkinson's disease reported to be reversed; patients should be carefully observed for…
- Papaverine + Carbidopa Tablets— Beneficial effects of levodopa in Parkinson's disease may be reversed; patients should be carefully observed for loss of…
- Papaverine + Foscarbidopa/Foslevodopa— Dopamine D2 receptor antagonist may reduce effectiveness of foslevodopa. Monitor for worsening Parkinson's symptoms.