Isoproterenol Hydrochloride has 8 known drug interactions based on U.S. FDA drug labeling data. Of these, 1 are contraindicated combinations that should be avoided entirely. 7 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Epinephrine, Chlorpheniramine, Diphenhydramine. Patients taking Isoproterenol Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 8
- Contraindicated
- 1
- Major
- 7
Contraindicated (1)
- Isoproterenol Hydrochloride + Epinephrine— Both drugs are direct cardiac stimulants; combined effects may induce serious arrhythmias upon simultaneous administrati…
Major (7)
- Isoproterenol Hydrochloride + Chlorpheniramine— Antihistamine that may potentiate clinical response of isoproterenol.
- Isoproterenol Hydrochloride + Diphenhydramine— Antihistamine that may potentiate clinical response of isoproterenol.
- Isoproterenol Hydrochloride + Halothane— Avoid concurrent use due to potential to sensitize myocardium to sympathomimetic amine effects, increasing arrhythmia ri…
- Isoproterenol Hydrochloride + Levothyroxine Sodium— May potentiate clinical response of isoproterenol; hemodynamic parameters may be significantly affected.
- Isoproterenol Hydrochloride + Monoamine Oxidase Inhibitors (Maois)— May potentiate clinical response of isoproterenol; hemodynamic parameters may be significantly affected.
- Isoproterenol Hydrochloride + Propranolol— Beta-adrenergic blocking drug that antagonizes cardiostimulating and bronchodilating effects of isoproterenol.
- Isoproterenol Hydrochloride + Tripelennamine— Antihistamine that may potentiate clinical response of isoproterenol.