Pindolol has 7 known drug interactions based on U.S. FDA drug labeling data. Of these, 1 are contraindicated combinations that should be avoided entirely. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Thioridazine Hydrochloride, Epinephrine, Reserpine. Patients taking Pindolol should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 7
- Contraindicated
- 1
- Major
- 2
- Moderate
- 1
- Minor
- 3
Contraindicated (1)
- Pindolol + Thioridazine Hydrochloride— Produces moderate, dose-related increases in thioridazine and metabolite serum levels, with elevated pindolol levels. Sh…
Major (2)
- Pindolol + Epinephrine— Patients with history of severe anaphylactic reactions may be unresponsive to usual epinephrine doses and more reactive …
- Pindolol + Reserpine— Additive hypotensive and bradycardic effects; may produce vertigo, syncope, or postural hypotension. Close observation r…
Moderate (1)
- Pindolol + Thioridazine— Pindolol increases serum thioridazine levels; pindolol levels may also be increased with coadministration. Monitor thera…
Minor (3)
- Pindolol + Guanethidine— Used together without unexpected adverse interactions in clinical practice.
- Pindolol + Hydralazine— Used together without unexpected adverse interactions in clinical practice.
- Pindolol + Hydrochlorothiazide— Used together without unexpected adverse interactions in clinical practice.