Delavirdine Interactions

Etravirine and delavirdine should not be co-administered. Combining two NNRTIs has not been shown to be beneficial.

Source: NLP:etravirine

Delavirdine increases rifabutin AUC by 230% and Cmax by 128%, while rifabutin reduces delavirdine concentrations by 80%. Interaction is contraindicated.

Source: NLP:rifabutin

Strong CYP3A4 inhibitor that significantly increases nimodipine plasma concentration and blood pressure lowering effect. Concomitant administration should generally be avoided.

Source: NLP:nimodipine

CYP3A4 inhibitor that increases plasma levels of carbamazepine; dose adjustment and/or plasma level monitoring may be necessary.

Source: NLP:carbamazepine

CYP2D6 inhibitor that may increase blood levels of propranolol.

Source: NLP:propranolol hydrochloride

Delavirdine absorption may be impaired with ranitidine due to increased gastric pH. Chronic H2-receptor antagonist use with delavirdine not recommended.

Source: NLP:ranitidine