Rosiglitazone Interactions

Gemfibrozil is a strong CYP2C8 inhibitor that may increase rosiglitazone exposure; dosing reduction may be required.

Source: NLP:gemfibrozil

Exposure to rosiglitazone may be increased when coadministered with leflunomide. Monitor and adjust dose as required.

Source: NLP:leflunomide

CYP2C8 substrate; caution should be exercised when administering paclitaxel concomitantly.

Source: NLP:paclitaxel

BACTRIM potentiates oral hypoglycemic effects of rosiglitazone. Additional blood glucose monitoring warranted.

Source: NLP:sulfamethoxazole and trimethoprim

Teriflunomide may increase exposure of rosiglitazone. Monitor patients and adjust dose as required.

Source: NLP:teriflunomide