Ursodiol has 6 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Antacids Containing Aluminum, Cholestyramine Light, Clofibrate. Patients taking Ursodiol should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 6
- Moderate
- 6
Moderate (6)
- Ursodiol + Antacids Containing Aluminum— May interfere with ursodiol action by adsorbing bile acids and reducing ursodiol absorption.
- Ursodiol + Cholestyramine Light— Bile acid sequestering agent that may interfere with ursodiol action by reducing its absorption.
- Ursodiol + Clofibrate— Increases hepatic cholesterol secretion and may counteract the effectiveness of ursodiol.
- Ursodiol + Colestipol— Bile acid sequestering agent that may interfere with ursodiol action by reducing its absorption.
- Ursodiol + Estrogens— Increase hepatic cholesterol secretion and may counteract the effectiveness of ursodiol.
- Ursodiol + Oral Contraceptives— Increase hepatic cholesterol secretion and may counteract the effectiveness of ursodiol.