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Macrolide Antibiotics (E.G., Erythromycin)

Also known as: E.E.S.

Check Macrolide Antibiotics (E.G., Erythromycin) Interactions →

2 interactions on record

Macrolide Antibiotics (E.G., Erythromycin) has 2 known drug interactions based on U.S. FDA drug labeling data. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Benzhydrocodone And Acetaminophen, Oxycodone Hydrochloride. Patients taking Macrolide Antibiotics (E.G., Erythromycin) should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 2
Major: 2

Major (2)

Macrolide Antibiotics (E.G., Erythromycin) + Benzhydrocodone And Acetaminophen— CYP3A4 inhibitors increase hydrocodone plasma concentration, resulting in increased or prolonged opioid effects includin…
Macrolide Antibiotics (E.G., Erythromycin) + Oxycodone Hydrochloride— CYP3A4 inhibitors increase plasma concentration of oxycodone, resulting in increased or prolonged opioid effects, respir…

Macrolide Antibiotics (E.G., Erythromycin) + Benzhydrocodone And Acetaminophen⚠️Major

CYP3A4 inhibitors increase hydrocodone plasma concentration, resulting in increased or prolonged opioid effects including respiratory depression and sedation.

Macrolide Antibiotics (E.G., Erythromycin) + Oxycodone Hydrochloride⚠️Major

CYP3A4 inhibitors increase plasma concentration of oxycodone, resulting in increased or prolonged opioid effects, respiratory depression, and sedation.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.