Propoxyphene Interactions

Serious, sometimes fatal reactions reported with concomitant use of opioid drugs and MAOIs, including selective MAO-B inhibitors.

Source: NLP:safinamide mesylate

Decreased alprazolam maximum plasma concentration by 6%, decreased clearance by 38%, and increased half-life by 58%.

Source: NLP:alprazolam

CYP3A4 inhibitor that increases carbamazepine plasma levels; close monitoring and dosage adjustment may be required.

Source: NLP:carbamazepine

May increase glucose-lowering effect of glimepiride, increasing susceptibility to and/or intensity of hypoglycemia.

Source: NLP:glimepiride

May increase glucose-lowering effect of glipizide and susceptibility to hypoglycemia; monitor closely.

Source: NLP:glipizide

May increase risk of hypoglycemia. Repaglinide dose reductions and increased glucose monitoring may be required.

Source: NLP:repaglinide

Administered without adverse drug interaction in limited clinical experience.

Source: NLP:prazosin hydrochloride