Seville Oranges Interactions

Strong CYP3A inhibitor. Increases nirogacestat exposure, which may increase risk of adverse reactions.

Source: NLP:nirogacestat

Contains strong or moderate CYP3A inhibitors. Should be avoided during ibrutinib treatment to prevent increased ibrutinib concentrations.

Source: NLP:ibrutinib

Seville oranges are strong CYP3A inhibitors. Concomitant use increases rilzabrutinib exposure and risk of adverse reactions.

Source: NLP:rilzabrutinib