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Iron Supplements

23 interactions on record

Iron Supplements has 23 known drug interactions based on U.S. FDA drug labeling data. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Cefdinir, Ciprofloxacin, Acetohydroxamic Acid. Patients taking Iron Supplements should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 23
Major: 2
Moderate: 21

Major (2)

Iron Supplements + Cefdinir— Reduces cefdinir absorption by 80% when given with 60 mg elemental iron supplement. Take cefdinir at least 2 hours befor…
Iron Supplements + Ciprofloxacin— Products containing iron may substantially decrease ciprofloxacin absorption, resulting in serum and urine levels consid…

Moderate (21)

Iron Supplements + Acetohydroxamic Acid— AHA chelates iron, reducing absorption of both drugs from the intestinal lumen when taken concomitantly. Intramuscular i…
Iron Supplements + Deferiprone— Polyvalent cation that may bind deferiprone. Allow at least 4-hour interval between administration.
Iron Supplements + Delafloxacin Meglumine— Iron metal cations form chelates with delafloxacin, substantially interfering with absorption and resulting in considera…
Iron Supplements + Doxycycline Hyclate— Iron-containing preparations impair absorption of tetracyclines.
Iron Supplements + Levofloxacin— Metal cation may interfere with gastrointestinal absorption of levofloxacin when taken within 2 hours, resulting in lowe…
Iron Supplements + Moxifloxacin— Decreased moxifloxacin absorption due to chelation with multivalent cations. Take moxifloxacin at least 4 hours before o…
Iron Supplements + Moxifloxacin Hydrochloride— Metal cations interfere with moxifloxacin absorption. Take moxifloxacin at least 4 hours before or 8 hours after multivi…
Iron Supplements + Moxifloxacin Hydrochloride Tablets, 400 Mg— Metal cation iron forms chelates with moxifloxacin, substantially interfering with its absorption. Take moxifloxacin at …
Iron Supplements + Ofloxacin— Divalent cations from iron form chelates with ofloxacin, substantially interfering with absorption and resulting in cons…
Iron Supplements + Polyethylene Glycol 3350, Sodium Sulfate, Potassium Chloride, Magnesium Sulfate, And Sodium Chloride For Oral Solution— SUFLAVE can reduce absorption of iron. Administer at least 2 hours before and not less than 6 hours after SUFLAVE to avo…
Iron Supplements + Sodium Picosulfate, Magnesium Oxide, And Anhydrous Citric Acid— Reduced absorption of iron due to chelation with magnesium. Administer at least 2 hours before and not less than 6 hours…
Iron Supplements + Sodium Sulfate Anhydrous, Potassium Sulfate, And Magnesium Sulfate— Sodium sulfate, potassium sulfate, and magnesium sulfate oral solution can reduce absorption of iron via chelation with …
Iron Supplements + Sodium Sulfate, Magnesium Sulfate, And Potassium Chloride— Reduced absorption due to chelation with magnesium. Administer at least 2 hours before and not less than 6 hours after S…
Iron Supplements + Sodium Sulfate, Potassium Sulfate, Magnesium Sulfate— Administer at least 2 hours before and not less than 6 hours after SUPREP to avoid chelation with magnesium and reduced …
Iron Supplements + Technetium Tc 99m Medronate— High levels of iron may alter biodistribution of technetium Tc 99m medronate, reducing skeletal uptake and increasing ex…
Iron Supplements + Technetium Tc 99m Oxidronate— High levels of iron may alter biodistribution of technetium Tc 99m oxidronate, reducing skeletal uptake and increasing e…
Iron Supplements + Technetium Tc 99m Pyrophosphate— High levels of iron from concomitant iron infusions may alter biodistribution of technetium Tc 99m pyrophosphate, reduci…
Iron Supplements + Tetracycline Hydrochloride— Iron preparations impair absorption of tetracycline.
Iron Supplements + Trientine Hydrochloride— Iron and trientine hydrochloride each inhibit absorption of the other. Two hours should elapse between administration of…
Iron Supplements + Trientine Tetrahydrochloride— Iron and CUVRIOR (trientine) each inhibit absorption of the other. Separate administration by at least 2 hours.
Iron Supplements + Vitamin C, Zinc, Arnica Montana Extract, Bromelain, Diosmin, Rutin, Citrus Bioflavonoids, Hesperidin Methyl Chalcone— High doses of zinc can interfere with the absorption of iron supplements.

Iron Supplements + Cefdinir⚠️Major

Reduces cefdinir absorption by 80% when given with 60 mg elemental iron supplement. Take cefdinir at least 2 hours before or after iron supplement.

Iron Supplements + Ciprofloxacin⚠️Major

Products containing iron may substantially decrease ciprofloxacin absorption, resulting in serum and urine levels considerably lower than desired.

Iron Supplements + Acetohydroxamic Acid🟡Moderate

AHA chelates iron, reducing absorption of both drugs from the intestinal lumen when taken concomitantly. Intramuscular iron is recommended when iron administration is needed.

Iron Supplements + Deferiprone🟡Moderate

Polyvalent cation that may bind deferiprone. Allow at least 4-hour interval between administration.

Iron Supplements + Delafloxacin Meglumine🟡Moderate

Iron metal cations form chelates with delafloxacin, substantially interfering with absorption and resulting in considerably lower systemic concentrations.

Iron Supplements + Doxycycline Hyclate🟡Moderate

Iron-containing preparations impair absorption of tetracyclines.

Iron Supplements + Levofloxacin🟡Moderate

Metal cation may interfere with gastrointestinal absorption of levofloxacin when taken within 2 hours, resulting in lower systemic levels.

Iron Supplements + Moxifloxacin🟡Moderate

Decreased moxifloxacin absorption due to chelation with multivalent cations. Take moxifloxacin at least 4 hours before or 8 hours after multivitamins.

Iron Supplements + Moxifloxacin Hydrochloride🟡Moderate

Metal cations interfere with moxifloxacin absorption. Take moxifloxacin at least 4 hours before or 8 hours after multivitamins.

Iron Supplements + Moxifloxacin Hydrochloride Tablets, 400 Mg🟡Moderate

Metal cation iron forms chelates with moxifloxacin, substantially interfering with its absorption. Take moxifloxacin at least 4 hours before or 8 hours after iron-containing products.

Iron Supplements + Ofloxacin🟡Moderate

Divalent cations from iron form chelates with ofloxacin, substantially interfering with absorption and resulting in considerably lower systemic levels. Should not be taken within 2 hours before or after ofloxacin.

Iron Supplements + Polyethylene Glycol 3350, Sodium Sulfate, Potassium Chloride, Magnesium Sulfate, And Sodium Chloride For Oral Solution🟡Moderate

SUFLAVE can reduce absorption of iron. Administer at least 2 hours before and not less than 6 hours after SUFLAVE to avoid chelation with magnesium.

Iron Supplements + Sodium Picosulfate, Magnesium Oxide, And Anhydrous Citric Acid🟡Moderate

Reduced absorption of iron due to chelation with magnesium. Administer at least 2 hours before and not less than 6 hours after CLENPIQ.

Iron Supplements + Sodium Sulfate Anhydrous, Potassium Sulfate, And Magnesium Sulfate🟡Moderate

Sodium sulfate, potassium sulfate, and magnesium sulfate oral solution can reduce absorption of iron via chelation with magnesium. Administer iron at least 2 hours before and not less than 6 hours after this product.

Iron Supplements + Sodium Sulfate, Magnesium Sulfate, And Potassium Chloride🟡Moderate

Reduced absorption due to chelation with magnesium. Administer at least 2 hours before and not less than 6 hours after SUTAB.

Iron Supplements + Sodium Sulfate, Potassium Sulfate, Magnesium Sulfate🟡Moderate

Administer at least 2 hours before and not less than 6 hours after SUPREP to avoid chelation with magnesium and reduced absorption.

Iron Supplements + Technetium Tc 99m Medronate🟡Moderate

High levels of iron may alter biodistribution of technetium Tc 99m medronate, reducing skeletal uptake and increasing extraosseous uptake, potentially degrading imaging quality.

Iron Supplements + Technetium Tc 99m Oxidronate🟡Moderate

High levels of iron may alter biodistribution of technetium Tc 99m oxidronate, reducing skeletal uptake and increasing extraosseous uptake, potentially degrading imaging quality.

Iron Supplements + Technetium Tc 99m Pyrophosphate🟡Moderate

High levels of iron from concomitant iron infusions may alter biodistribution of technetium Tc 99m pyrophosphate, reducing skeletal uptake and increasing extraosseous uptake, potentially degrading imaging quality.

Iron Supplements + Tetracycline Hydrochloride🟡Moderate

Iron preparations impair absorption of tetracycline.

Iron Supplements + Trientine Hydrochloride🟡Moderate

Iron and trientine hydrochloride each inhibit absorption of the other. Two hours should elapse between administration of trientine hydrochloride capsules and iron.

Iron Supplements + Trientine Tetrahydrochloride🟡Moderate

Iron and CUVRIOR (trientine) each inhibit absorption of the other. Separate administration by at least 2 hours.

Iron Supplements + Vitamin C, Zinc, Arnica Montana Extract, Bromelain, Diosmin, Rutin, Citrus Bioflavonoids, Hesperidin Methyl Chalcone🟡Moderate

High doses of zinc can interfere with the absorption of iron supplements.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.