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Clindamycin Palmitate Hydrochloride

Also known as: Clindamycin Palmitate Hydrochloride (Pediatric)

Route: Oral

Check Clindamycin Palmitate Hydrochloride Interactions →

4 interactions on record⛔ Black Box Warning

Clindamycin Palmitate Hydrochloride has 4 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Adrenergic Blockers, Mao Inhibitors, Rifampin. Patients taking Clindamycin Palmitate Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 4
Moderate: 3
Minor: 1

Moderate (3)

Clindamycin Palmitate Hydrochloride + Adrenergic Blockers— Clindamycin has neuromuscular blocking properties that may enhance the action of neuromuscular blocking agents; use with…
Clindamycin Palmitate Hydrochloride + Mao Inhibitors— Strong CYP3A4 inhibitors may increase plasma concentrations of clindamycin; monitor for adverse reactions.
Clindamycin Palmitate Hydrochloride + Rifampin— Strong CYP3A4 inducer may reduce plasma concentrations of clindamycin and decrease effectiveness; monitor for loss of ef…

Minor (1)

Clindamycin Palmitate Hydrochloride + Clindamycin— Drug Interactions Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of ot…

Clindamycin Palmitate Hydrochloride + Adrenergic Blockers🟡Moderate

Clindamycin has neuromuscular blocking properties that may enhance the action of neuromuscular blocking agents; use with caution.

Clindamycin Palmitate Hydrochloride + Mao Inhibitors🟡Moderate

Strong CYP3A4 inhibitors may increase plasma concentrations of clindamycin; monitor for adverse reactions.

Clindamycin Palmitate Hydrochloride + Rifampin🟡Moderate

Strong CYP3A4 inducer may reduce plasma concentrations of clindamycin and decrease effectiveness; monitor for loss of effectiveness.

Clindamycin Palmitate Hydrochloride + Clindamycin🟢Minor

Drug Interactions Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Clindamycin is metabolized predominantly by CYP3A4, and to a lesser extent by CYP3A5, to the major metabolite clindamycin sulfoxide and minor metabolite N-desmethylclindamycin. Therefore inhibitors of CYP3A4 and CYP3A5 may increase plasma concentrations of clindamycin and inducers of these isoenzymes may reduce plasma concentrations of clindamycin.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.