Mecamylamine Hydrochloride has 4 known drug interactions based on U.S. FDA drug labeling data. Of these, 2 are contraindicated combinations that should be avoided entirely. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Acetazolamide, Macrolide Antibiotics, Alcohol. Patients taking Mecamylamine Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 4
- Contraindicated
- 2
- Major
- 2
Contraindicated (2)
- Mecamylamine Hydrochloride + Acetazolamide— Patients receiving sulfonamides generally should not be treated with Mecamylamine HCl (ganglion blocker).
- Mecamylamine Hydrochloride + Macrolide Antibiotics— Patients receiving antibiotics generally should not be treated with Mecamylamine HCl (ganglion blocker).
Major (2)
- Mecamylamine Hydrochloride + Alcohol— Alcohol may potentiate the action of Mecamylamine HCl.
- Mecamylamine Hydrochloride + Topical Local Anesthetics— Anesthesia may potentiate the action of Mecamylamine HCl.