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Sodium Iodide I 131

Also known as: Sodium Iodide I 131 Diagnostic

Route: Oral

Check Sodium Iodide I 131 Interactions →

13 interactions on record

Sodium Iodide I 131 has 13 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Bone Marrow Depressants, Amiodarone, Carbimazole. Patients taking Sodium Iodide I 131 should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 13
Major: 1
Moderate: 11

Major (1)

Sodium Iodide I 131 + Bone Marrow Depressants— Concomitant use may enhance depression of the hematopoietic system caused by large doses of sodium iodide I 131.

Moderate (11)

Sodium Iodide I 131 + Amiodarone— Drug that interferes with accumulation of radioiodide by the thyroid. Discontinue 6 months before procedure.
Sodium Iodide I 131 + Carbimazole— Thionamide medication that interferes with accumulation of radioiodide by the thyroid. Discontinue 3 days before procedu…
Sodium Iodide I 131 + Levothyroxine— Natural or synthetic thyroid hormone that interferes with radioiodide accumulation. Discontinue 4 weeks before procedure…
Sodium Iodide I 131 + Lugol Solution— Iodide-containing agent that interferes with radioiodide accumulation. Discontinue 3 weeks before procedure.
Sodium Iodide I 131 + Methimazole— Thionamide medication that interferes with accumulation of radioiodide by the thyroid. Discontinue 3 days before procedu…
Sodium Iodide I 131 + Oral Cholecystographic Contrast Agents— Radiographic contrast agent that interferes with radioiodide accumulation. Discontinue 6 months before procedure.
Sodium Iodide I 131 + Potassium Iodide— Interferes with accumulation of radioiodide by the thyroid; discontinue 3 weeks before procedure.
Sodium Iodide I 131 + Propylthiouracil— Thionamide medication that interferes with accumulation of radioiodide by the thyroid. Discontinue 3 days before procedu…
Sodium Iodide I 131 + Saturated Solution Of Potassium Iodide— Iodide-containing agent that interferes with radioiodide accumulation. Discontinue 3 weeks before procedure.
Sodium Iodide I 131 + Triiodothyronine— Natural or synthetic thyroid hormone that interferes with radioiodide accumulation. Discontinue 2 weeks before procedure…
Sodium Iodide I 131 + Water Soluble Intravenous Radiographic Contrast Agents— Radiographic contrast agent that interferes with radioiodide accumulation. Discontinue 2 months before procedure.

Sodium Iodide I 131 + Bone Marrow Depressants⚠️Major

Concomitant use may enhance depression of the hematopoietic system caused by large doses of sodium iodide I 131.

Sodium Iodide I 131 + Amiodarone🟡Moderate

Drug that interferes with accumulation of radioiodide by the thyroid. Discontinue 6 months before procedure.

Sodium Iodide I 131 + Carbimazole🟡Moderate

Thionamide medication that interferes with accumulation of radioiodide by the thyroid. Discontinue 3 days before procedure.

Sodium Iodide I 131 + Levothyroxine🟡Moderate

Natural or synthetic thyroid hormone that interferes with radioiodide accumulation. Discontinue 4 weeks before procedure.

Sodium Iodide I 131 + Lugol Solution🟡Moderate

Iodide-containing agent that interferes with radioiodide accumulation. Discontinue 3 weeks before procedure.

Sodium Iodide I 131 + Methimazole🟡Moderate

Thionamide medication that interferes with accumulation of radioiodide by the thyroid. Discontinue 3 days before procedure.

Sodium Iodide I 131 + Oral Cholecystographic Contrast Agents🟡Moderate

Radiographic contrast agent that interferes with radioiodide accumulation. Discontinue 6 months before procedure.

Sodium Iodide I 131 + Potassium Iodide🟡Moderate

Interferes with accumulation of radioiodide by the thyroid; discontinue 3 weeks before procedure.

Sodium Iodide I 131 + Propylthiouracil🟡Moderate

Thionamide medication that interferes with accumulation of radioiodide by the thyroid. Discontinue 3 days before procedure.

Sodium Iodide I 131 + Saturated Solution Of Potassium Iodide🟡Moderate

Iodide-containing agent that interferes with radioiodide accumulation. Discontinue 3 weeks before procedure.

Sodium Iodide I 131 + Triiodothyronine🟡Moderate

Natural or synthetic thyroid hormone that interferes with radioiodide accumulation. Discontinue 2 weeks before procedure.

Sodium Iodide I 131 + Water Soluble Intravenous Radiographic Contrast Agents🟡Moderate

Radiographic contrast agent that interferes with radioiodide accumulation. Discontinue 2 months before procedure.

Sodium Iodide I 131 + Ethionamideℹ️Unknown

Table 4 Pharmaceuticals / OTCs / Agents Blocking Radioiodine Uptake Type of Medication Recommended time of withdrawal Thionamide medications (e.g., propylthiouracil, methimazole, carbimazole) 3 days Multivitamins containing iodide 10 days Natural or synthetic thyroid hormones triiodothyronine thyroxine 2 weeks 4 weeks Iodide-containing foods: iodized salt, dairy products, egg yolks, seafood, turkey and liver 2 weeks Kelp, agar, carrageenan, Lugol solution 3 weeks Saturated solution of potassium iodide 3 weeks Topical iodide (e.g., surgical skin preparation) 3 weeks Intravenous radiographic contrast agents Water soluble Lipophilic 2 months 6 months Amiodarone 6 months Many pharmacologic agents are known to interact with radioiodide.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.