Simethicone

4 interactions on record

Simethicone has 4 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Fosinopril, Fosinopril Sodium, Fosinopril Sodium And Hydrochlorothiazide. Patients taking Simethicone should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 4
Moderate: 4

Moderate (4)

Simethicone + Fosinopril— Antacid reduces serum levels and urinary excretion of fosinoprilat. Separate dosing by 2 hours if concomitant use is nee…
Simethicone + Fosinopril Sodium— Reduces serum levels and urinary excretion of fosinoprilat. Dosing should be separated by 2 hours.
Simethicone + Fosinopril Sodium And Hydrochlorothiazide— Antacid component may impair absorption of fosinopril; dosing should be separated by 2 hours if concomitant use is neces…
Simethicone + Levothyroxine Sodium— May affect intragastric pH and reduce levothyroxine absorption. Monitor patients appropriately.

Simethicone + Fosinopril🟡Moderate

Antacid reduces serum levels and urinary excretion of fosinoprilat. Separate dosing by 2 hours if concomitant use is needed.

Simethicone + Fosinopril Sodium🟡Moderate

Reduces serum levels and urinary excretion of fosinoprilat. Dosing should be separated by 2 hours.

Simethicone + Fosinopril Sodium And Hydrochlorothiazide🟡Moderate

Antacid component may impair absorption of fosinopril; dosing should be separated by 2 hours if concomitant use is necessary.

Simethicone + Levothyroxine Sodium🟡Moderate

May affect intragastric pH and reduce levothyroxine absorption. Monitor patients appropriately.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.