Does Adalimumab Adbm Interact with Cyclosporine?
CDI records a moderate classification for Adalimumab Adbm and Cyclosporine. The stored summary is: CYP450 enzyme formation may be suppressed by adalimumab-adbm. Monitoring of drug concentration recommended upon initiation or discontinuation. The mechanism involves suppression of cyp450 enzyme formation by tnf antagonist. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Cyclosporine Class
- Calcineurin Inhibitor Immunosuppressant
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Suppression of CYP450 enzyme formation by TNF antagonist
What To Tell Your Doctor or Pharmacist
If you are taking Adalimumab Adbm and your doctor is considering prescribing Cyclosporine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider