Does Angiotensin Ii Interact with Alteplase?
CDI records a moderate classification for Angiotensin Ii and Alteplase. The stored summary is: Concomitant angiotensin-converting enzyme inhibitors may increase the risk of angioedema, particularly in patients with acute ischemic stroke. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Angiotensin Ii Class
- Vasoconstrictor
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Angiotensin Ii and your doctor is considering prescribing Alteplase (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider