Does Angiotensin Ii Interact with Piroxicam?
CDI records a moderate classification for Angiotensin Ii and Piroxicam. The stored summary is: May diminish antihypertensive effect and in elderly, volume depleted, or renally impaired patients may result in renal function deterioration. The mechanism involves reduced antihypertensive efficacy and renal hemodynamic changes. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Angiotensin Ii Class
- Vasoconstrictor
- Piroxicam Class
- Nonsteroidal Anti-inflammatory Drug
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Reduced antihypertensive efficacy and renal hemodynamic changes
What To Tell Your Doctor or Pharmacist
If you are taking Angiotensin Ii and your doctor is considering prescribing Piroxicam (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider