Does Antacids Containing Aluminum Interact with Usodiol?
Antacids Containing Aluminum and Usodiol have a moderate drug interaction according to U.S. FDA drug labeling data. May interfere with ursodiol action by adsorbing bile acids, similar to bile acid sequestering agents. The mechanism involves adsorbs bile acids in vitro. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Usodiol Class
- Bile Acid
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Antacids Containing Aluminum and Usodiol occurs because adsorbs bile acids in vitro. Clinically, this means may interfere with ursodiol action by adsorbing bile acids, similar to bile acid sequestering agents. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Antacids Containing Aluminum and your doctor is considering prescribing Usodiol (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider