Does Antacids Containing Calcium Interact with Etodolac?
Antacids Containing Calcium and Etodolac have a minor drug interaction according to U.S. FDA drug labeling data. Antacids can decrease peak concentration of etodolac by 15-20% but have no effect on time-to-peak or extent of absorption. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Minor
- Etodolac Class
- Nonsteroidal Anti-inflammatory Drug
- Management
- Generally manageable
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Antacids Containing Calcium and your doctor is considering prescribing Etodolac (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider