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Does Azithromycin Interact with Simvastatin?

No documented interaction between Azithromycin and Simvastatin was found in our FDA drug labeling database. This does not guarantee the combination is safe for every patient — drug interaction databases are updated periodically as new information becomes available. Always consult your pharmacist or physician before combining medications. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
None
Simvastatin Class
HMG-CoA Reductase Inhibitor
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA
💊 Azithromycin(Zithromax)+💊 Simvastatin(Flolipid)

Severity & Interaction Details

✅
none
No interaction documented
We found no documented interaction between these two drugs in the FDA labeling data.
Severity scale
MinorContra
On record
Not found
Drug A class
—
Drug B class
HMG-CoA Reductase Inhibitor
Source
—

✅ No documented interaction in our FDA-label dataset.

This means no interaction between Azithromycin and Simvastatin was surfaced from openFDA or NIH NLM sources. It does not guarantee the combination is safe for every patient — always confirm with your pharmacist.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.