Barbiturates + Promethazine Hydrochloride And Phenylephrine Hydrochloride Interaction
Moderateinteraction on record
Description
Promethazine may increase, prolong, or intensify sedative action; dose of barbiturates should be reduced by at least one-half.
Mechanism
CNS depression potentiation
Source: NLP:promethazine hydrochloride and phenylephrine hydrochloride