Does Benzocaine Butamben And Tetracaine Hydrochloride Interact with Metoclopramide?
CDI records a major classification for Benzocaine Butamben And Tetracaine Hydrochloride and Metoclopramide. The stored summary is: Increased risk of methemoglobinemia when concurrently exposed to this oxidizing agent with local anesthetics. The mechanism involves oxidation of hemoglobin to methemoglobin. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Benzocaine Butamben And Tetracaine Hydrochloride Class
- Standardized Chemical Allergen
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Oxidation of hemoglobin to methemoglobin
What To Tell Your Doctor or Pharmacist
If you are taking Benzocaine Butamben And Tetracaine Hydrochloride and your doctor is considering prescribing Metoclopramide (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider