HomeButalbital Aspirin Caffeine And Codeine PhosphateButalbital Aspirin Caffeine And Codeine Phosphate + Oxycodone

Does Butalbital Aspirin Caffeine And Codeine Phosphate Interact with Oxycodone?

Butalbital Aspirin Caffeine And Codeine Phosphate and Oxycodone have a minor drug interaction according to U.S. FDA drug labeling data. If urgent use of an opioid is necessary, use test doses and frequent titration of small doses of other opioids (such as oxycodone, hydrocodone, oxymorphone, or buprenorphine) to treat pain while closely monitoring blood pressure and signs and symptoms of CNS and respiratory depression. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Minor
Butalbital Aspirin Caffeine And Codeine Phosphate Class
Nonsteroidal Anti-inflammatory Drug
Oxycodone Class
Opioid Agonist
Management
Generally manageable
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Butalbital Aspirin Caffeine And Codeine Phosphate and your doctor is considering prescribing Oxycodone (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Butalbital Aspirin Caffeine And Codeine Phosphate(Butalbital, Aspirin, Caffeine And Codeine Phosphate)+💊 Oxycodone

Severity & Interaction Details

minor
Generally safe — minor interaction
Low clinical significance. Routine awareness is usually sufficient.
Severity scale
MinorContra
On record
Yes
Drug A class
Nonsteroidal Anti-inflammatory Drug
Drug B class
Opioid Agonist
Source
FDA drug label - butalbital, aspirin, caffeine and codeine phosphate

What this means in plain English

If urgent use of an opioid is necessary, use test doses and frequent titration of small doses of other opioids (such as oxycodone, hydrocodone, oxymorphone, or buprenorphine) to treat pain while closely monitoring blood pressure and signs and symptoms of CNS and respiratory depression.

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Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.