Does Clarithromycin Interact with Ritonavir 100 Mg?
Clarithromycin and Ritonavir 100 Mg have a unknown drug interaction according to U.S. FDA drug labeling data. Anti-infective: clarithromycin ↑ clarithromycin For patients with renal impairment, adjust clarithromycin dose as follows: • For patients with CL CR 30 to 60 mL per min the dose of clarithromycin should be reduced by 50%. • For patients with CL CR less than 30 mL per min the dose of clarithromycin should be decreased by 75%. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Clarithromycin Class
- Macrolide Antimicrobial
- Ritonavir 100 Mg Class
- Cytochrome P450 3A Inhibitor
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Clarithromycin and your doctor is considering prescribing Ritonavir 100 Mg (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider