Cobicistat + Ritonavir Interaction

Unknowninteraction on record

Description

Use of TYBOST with lopinavir is not recommended because lopinavir is co-formulated with ritonavir. In addition to the drug interactions noted in Table 7 , TYBOST is not recommended for use in combination with fixed-dose combination tablets that contain cobicistat, lopinavir/ritonavir or regimens containing ritonavir, or in combination with more than one antiretroviral agent that requires pharmacokinetic enhancement [see Warnings and Precautions (5.4) ]. Switching from ritonavir to TYBOST coadministered with atazanavir or darunavir: Maintain bosentan dose.

Source: FDA drug label - cobicistat