Does Colchicine Interact with Gemfibrozil?
Colchicine and Gemfibrozil have a moderate drug interaction according to U.S. FDA drug labeling data. Other lipid-lowering drug that may interact with colchicine. Monitor patients during coadministration. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Colchicine Class
- Alkaloid
- Gemfibrozil Class
- Peroxisome Proliferator Receptor alpha Agonist
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Colchicine and your doctor is considering prescribing Gemfibrozil (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider