Conivaptan + Erlotinib Hydrochloride Interaction
Majorinteraction on record
Description
Strong CYP3A4 inhibitor that increases erlotinib exposure and risk of exposure-related toxicity. Avoid co-administration or reduce erlotinib dosage if unavoidable.
Mechanism
Inhibition of CYP3A4 metabolism
Source: NLP:erlotinib hydrochloride