Conjugated Estrogens And Medroxyprogesterone Acetate + Medroxyprogesterone Interaction
Unknowninteraction on record
Description
• Inducers and/or inhibitors of CYP3A4 may affect estrogen drug metabolism ( 7.1 ) • Aminoglutethimide administered concomitantly with MPA may significantly depress the bioavailability of medroxyprogesterone acetate ( 7.1 ) 7.1 Metabolic Interactions In vitro and in vivo studies have shown that estrogens are metabolized partially by cytochrome P450 3A4 (CYP3A4).
Source: FDA drug label - conjugated estrogens and medroxyprogesterone acetate