Does Cyp3a Inducers Interact with Amlodipine Besylate And Olmesartan Medoxomil?
CDI records a moderate classification for Cyp3a Inducers and Amlodipine Besylate And Olmesartan Medoxomil. The stored summary is: Co-administration with amlodipine may reduce amlodipine efficacy. Closely monitor blood pressure when co-administered. The mechanism involves cyp3a inducers decrease amlodipine exposure. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
CYP3A inducers decrease amlodipine exposure
What To Tell Your Doctor or Pharmacist
If you are taking Cyp3a Inducers and your doctor is considering prescribing Amlodipine Besylate And Olmesartan Medoxomil (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider