Dextromethorphan + Desvenlafaxine Er Interaction
Moderateinteraction on record
Description
Desvenlafaxine increases dextromethorphan exposure. Reduce dose by up to one-half with 400 mg desvenlafaxine; no adjustment needed with 100 mg or lower.
Mechanism
CYP2D6 inhibition
Source: NLP:desvenlafaxine er