Does Digitalis Glycosides Interact with Dorzolamide Hydrochloride And Timolol Maleate Ophthalmic Sol?
Digitalis Glycosides and Dorzolamide Hydrochloride And Timolol Maleate Ophthalmic Sol have a moderate drug interaction according to U.S. FDA drug labeling data. May have additive effects in prolonging atrioventricular conduction time when used with beta-adrenergic blocking agents. The mechanism involves additive effects on av conduction. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Digitalis Glycosides and Dorzolamide Hydrochloride And Timolol Maleate Ophthalmic Sol occurs because additive effects on av conduction. Clinically, this means may have additive effects in prolonging atrioventricular conduction time when used with beta-adrenergic blocking agents. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Digitalis Glycosides and your doctor is considering prescribing Dorzolamide Hydrochloride And Timolol Maleate Ophthalmic Sol (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider