Diltiazem + Nifedipine Interaction

Moderateinteraction on record

Description

CYP3A inhibitor that increases nifedipine AUC by factors of 2.2 to 3.1 and C max by factors of 1.7 to 2.0. Caution should be exercised and dose reduction of nifedipine considered.

Mechanism

CYP3A inhibition

Source: NLP:nifedipine