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Does Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate Interact with Felodipine?

CDI records a unknown classification for Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate and Felodipine. The stored summary is: Others e.g., felodipine nicardipine nifedipine verapamil ↓ calcium channel blocker No data are available on the potential interactions of EFV with other calcium channel blockers that are substrates of CYP3A. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.

Severity: Unknown
Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate Class: Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor
Felodipine Class: Dihydropyridine Calcium Channel Blocker
Management: Consult your pharmacist
Data Source: U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate and your doctor is considering prescribing Felodipine (or vice versa), make sure to:

Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
Ask whether the benefits of combining these medications outweigh the risks for your specific situation
Ask what symptoms to watch for that would indicate the interaction is causing problems
Never stop or change either medication without first consulting your healthcare provider

💊 Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate(Atripla)+💊 Felodipine

Severity & Interaction Details

ℹ️

unknown

Interaction documented — severity unclassified

The CDI record includes an interaction but its severity has not been classified.

Severity scale

MinorContra

On record

Yes

Drug A class

Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor

Drug B class

Dihydropyridine Calcium Channel Blocker

Source

FDA drug label - efavirenz, emtricitabine and tenofovir disoproxil fumarate

What this means in plain English

Others e.g., felodipine nicardipine nifedipine verapamil ↓ calcium channel blocker No data are available on the potential interactions of EFV with other calcium channel blockers that are substrates of CYP3A.

About Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate and Felodipine

Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor, while Felodipine is a Dihydropyridine Calcium Channel Blocker. Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate is also sold under the brand name Atripla. Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate additionally carries an FDA boxed warning, the FDA's strongest safety alert.

Source and Limitations

This record was produced by automated extraction from drug-label information, including AI processing. The summary and mechanism are not verbatim FDA quotations. The drug profiles below may describe different formulations from the source label. Confirm the exact product and route with your pharmacist. This page does not establish independent clinical review.

📖 Source: FDA drug label - efavirenz, emtricitabine and tenofovir disoproxil fumarate

Recent research & FDA safety updates

Live

Auto-aggregated from PubMed E-utilities and FDA safety data.

PubMed

Hypertension in a randomized trial of dolutegravir- versus efavirenz-based antiretroviral therapy in pregnant and postpartum women with HIV.about Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate · 2026-04

PubMed

Hyperlipidemia and associated risk factors among people living with HIV on antiretroviral therapy: a retrospective cohort study from Eastern China.about Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate · 2026-04

PubMed

Efficacy and safety of bictegravir, emtricitabine, and tenofovir alafenamide (BIC/FTC/TAF) versus efavirenz, lamivudine, and tenofovir disoproxil fumarate (EFV+3TC + TDF) in late-presenting people with HIV rapid initial antiretroviral therapy.about Efavirenz Emtricitabine And Tenofovir Disoproxil Fumarate · 2026-03

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How this information is prepared: CDI uses automated extraction, including AI, to summarize drug labeling from openFDA and includes separately identified curated-reference records. RxNorm helps identify medications; it does not verify interaction claims. Extracted summaries and CDI severity classifications can contain errors and are not verbatim FDA statements or independent clinical review. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.