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Does Elbasvir And Grazoprevir Interact with Lovastatin?

Elbasvir And Grazoprevir and Lovastatin have a unknown drug interaction according to U.S. FDA drug labeling data. Fluvastatin Lovastatin Simvastatin ↑ fluvastatin ↑ lovastatin ↑ simvastatin Statin-associated adverse events such as myopathy should be closely monitored. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Elbasvir And Grazoprevir Class
Hepatitis C Virus NS5A Inhibitor
Lovastatin Class
HMG-CoA Reductase Inhibitor
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Elbasvir And Grazoprevir and your doctor is considering prescribing Lovastatin (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Elbasvir And Grazoprevir(Zepatier)+💊 Lovastatin(Altoprev)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Hepatitis C Virus NS5A Inhibitor
Drug B class
HMG-CoA Reductase Inhibitor
Source
FDA drug label - elbasvir and grazoprevir

What this means in plain English

Fluvastatin Lovastatin Simvastatin ↑ fluvastatin ↑ lovastatin ↑ simvastatin Statin-associated adverse events such as myopathy should be closely monitored.

About Elbasvir And Grazoprevir and Lovastatin

Elbasvir And Grazoprevir is a Hepatitis C Virus NS5A Inhibitor, while Lovastatin is a HMG-CoA Reductase Inhibitor. You may recognize them by the brand names Zepatier and Altoprev. Both medications are taken by mouth. Elbasvir And Grazoprevir additionally carries an FDA boxed warning, the FDA's strongest safety alert.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.