Does Emtricitabine And Tenofovir Alafenamide Interact with St Johns Wort?
CDI records a moderate classification for Emtricitabine And Tenofovir Alafenamide and St Johns Wort. The stored summary is: May decrease TAF concentration through P-gp and BCRP induction. The mechanism involves p-gp and bcrp induction. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Emtricitabine And Tenofovir Alafenamide Class
- Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
P-gp and BCRP induction
What To Tell Your Doctor or Pharmacist
If you are taking Emtricitabine And Tenofovir Alafenamide and your doctor is considering prescribing St Johns Wort (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider